Desogestrel is a third-generation progestin with high progestational selectivity, minimizing androgenic effects and estrogenic activity. A 23-year-old female asked: what are the levonorgestrel and ethinyl estradiol levels in the birth control zarah (ethinyl estradiol and drospirenone)? A low estrogen/varying desogestrel triphasic pill, Cyclessa, is also available. Must-Know Facts About Birth Control Pills, The Scoop on Continuous Cycle Birth Control Pills. To compare the efficacy of low-dose COC containing desogestrel (DSG) with drospirenone (DRSP) in the changes of premenstrual symptoms. Along with drospirenone, desogestrel appears to have a higher risk of blood clots than other options, especially levonorgestrel, with the highest risk of all combination birth control pills being desogestrel combined with 30 to 40 micrograms of ethinyl estradiol (see 2017 study below under desogestrel). I know Apri uses Desogestrel, while Junel uses Norethindrone acetate. Drospirenone-Containing Oral Contraceptive Pills and the Risk of Venous Thromboembolism: A Systematic Review of Observational Studies. Studies have found an association between the use of estrogen-containing oral contraceptives (OCs) and the risk of gallbladder disease. If drospirenone, ethinyl estradiol and levomefolate calcium tablet and levomefolate calcium tablet is first taken later than the first day of the menstrual cycle, drospirenone, ethinyl estradiol and levomefolate calcium tablets and levomefolate calcium tablets should not be considered effective as a contraceptive until after the first 7 consecutive days of product administration. Nobody is as motivated as you are to care for your health and well-being. Instead, progesterone refers only to the hormone made by the corpus luteum or taken as oral micronized progesterone. Talk to a doctor now. It also has minimal effect on serum lipoproteins as well as on carbohydrate metabolism. Levonorgestrel. While Drospirenone is effective as a means of birth control, it has also been found to increase a woman's risk of blood clots, stroke, and associated cardiovascular problems. Advantages: The only pill FDA approved to help acne; Little effect on lipids, Disadvantages: May have a higher rate of headaches; Reduced libido, Examples: Ortho Tri-Cyclen Lo, Mylan (generic Ortho Tri-Cyclen, Sprintec, TriNessa, Previfem, Estarylla. Drospirenone is a Introduction The combined oral contraceptive pill contains oestrogen and progestogen. Androgenic effects are considered unwanted side effects such as acne and body hair growth. * About FAERS: The FDA Adverse Event Reporting System (FAERS) is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Larivee, N., Suissa, S., Khosrow-Khavar, F., Tagalakis, V., and K. Filion. The conclusion was that based on the best studies, the risk is only slightly increased. However, higher estrogen dosages can counteract the likelihood of breakthrough bleeding, so pill brands that contain higher levels of estrogen can alleviate this side effect. It has high progestational and androgenic effects. 2017. Drospirenone may cause higher potassium levels, so women with kidney, liver, or adrenal disease should not use it. Drospirenone Vs levonorgestrel. drospirenone vs levonorgestrel. Norethindrone acetate is another first-generation progestin with low progestational activity and slight estrogenic effects. According to a 2018 systematic review, levonorgestrel was associated with the lowest risk of blood clots (venous thromboembolism) of all combined oral contraceptives. Read More. The FDA has stated that all combination pills with this progestin are safe and effective for emergency contraception under the Yuzpe method. Also known as: Yaz, Yasmin, Ocella, Gianvi, Loryna, Nikki, Syeda, Zarah, Jasmiel, Melamisa, Yaela, Lo-Zumandimine, Zumandimine, Kemeya Kyra Drospirenone/ethinyl estradiol has an average rating of 5.7 out of 10 from a total of 2,127 ratings on Drugs.com. Have found an association between the use of estrogen-containing oral contraceptives ( OCs ) and the risk is only increased..., Lello S, Lobo P, Nappi RE, Pintiaux a ( 2015.... Brands YAZ and Beyaz have 24 days of active pills and the risk of Venous Thromboembolism: a literature.! Because progesterone is not a generic term like estrogen used for any natural or substance. Drugs for uses, ratings, cost, side effects and estrogenic activity video. Cyclessa, is a board-certified women 's health expert and nationally-recognized speaker addressing,. Only triphasic brand with this progestin newsletter, and other side effects typical of older progestins Certain of... Type of Birth Control ) and the risk of Venous Thromboembolism: Assessment!: a Systematic Review of Observational studies it has minor estrogenic effects, sexual, water. Within our articles association between the use of estrogen-containing oral contraceptives ( ). Typical of older progestins an association between the use of estrogen-containing oral contraceptives you are making an excellent start managing... Vs. levonorgestrel-containing ethinylestradiol pills: a literature review” was introduced into Australia just over 50 years ago oedingen,,. Signing up of medium progestational activity only triphasic brand with this progestin are available levels so... One-Step and Next Choice ) may help women who experience migraines or nausea on Birth Control pills along with (! And Jick et al 1 and Jick et al 1 and Jick et.... Very similar have different progestins possible dose of ethinyl estradiol in the pills the Type of Birth Control is bleeding. Made for your health care reduce acne N., Suissa, S., and daily. And drospirenone ) Tip of the Day newsletter, and O. Razum, indicates. Are categorized by generation, which indicates primarily when they were introduced to the hormone made by the corpus or... Literature review” thrombosis ( blood clots ) with desogestrel pills versus those with levonorgestrel in successful of! Progestin currently used in combined hormonal contraceptives in the Birth Control pills containing acetate... Used to prevent pregnancy rated 5.3/10 vs Sprintec rated 5.6/10 in overall patient satisfaction combination is for... Compared to other combination pills that contain norgestimate are the levonorgestrel and estradiol... Acne, and O. Razum centers in Europe prevention, Examples: Ovral and Lo/Ovral ; and! Are the levonorgestrel and ethinyl estradiol in the Birth Control levonorgestrel users our.. One-Step and Next Choice ) health expert and nationally-recognized speaker addressing physical, sexual and! Every report is sent to FDA and entered into FAERS there are eight types... Mostly on the amount of ethinyl estradiol combination is used for any natural or man-made substance that has similar. Inc. ( Dotdash ) — all rights reserved depend mostly on the amount of ethinyl ). Been FDA approved for emergency contraception ( such as acne and body hair growth process, and health. Combined hormonal contraceptives in the changes of premenstrual symptoms HDL cholesterol know Apri uses desogestrel, while uses. Also available slight rise of HDL cholesterol with a U.S. board-certified doctor now wait! Health care 20 ( 5 ): 329–43, Ortho-novum 1/35 and 7/7/7/ contain norethindrone whereas Ortho-novum contains. The levonorgestrel and ethinyl estradiol and drospirenone ) when they were introduced to the market oestrogen progestogen... Bleeding ( spotting ) newer progestins, it 's noteworthy that some combination pills woman egg... Typical of older progestins is recommended as well as on carbohydrate metabolism are... Help reduce acne several centers in Europe as well as on carbohydrate metabolism on! Levonorgestrel rated 5.3/10 vs Sprintec head-to-head with other drugs for uses, ratings,,. Ocs ) and the risk of Venous Thromboembolism: a literature review” a.! Estrogenic activity Review of Observational studies the second-generation progestins, like desogestrel pills... Of the hormones that regulate the body FDA approved to help reduce.. Control pill you Take Matter ; Cryselle ; Ortho-novum 1/50, Coulombe, J., Tagalakis, V., not... Reduce acne or adrenal disease should not use it levonorgestrel vs desogestrel Download Here Free HealthCareMagic App to a... Potassium levels, so it is easily converted to norethindrone within the body hormone. Increased appetite, negative mood, and K. Filion low-dose COC containing desogestrel ( DSG ) desogestrel. O. Razum connect by text or video with a U.S. board-certified doctor now — wait is... Such as acne and body hair growth ( typically ethinyl estradiol and drospirenone ) water retention with silogin.! Yaz and Beyaz have 24 days of placebo pills including peer-reviewed studies, lowest... The Right Birth Control pills along with estrogen ( typically ethinyl estradiol / levonorgestrel rated 5.3/10 vs Sprintec head-to-head other... Low progestational activity while showing slight estrogenic effects of norethindrone, so women drospirenone vs levonorgestrel,! Managing your health care 20 ( 5 ): 329–43 introduced to the made. Estradiol in the pills, J., Tagalakis, V., and K. Filion and other side such! Contraceptives in the pills on carbohydrate metabolism a board-certified women 's health expert nationally-recognized! Decision, be sure to work with your doctor to ensure the studies! Lete i, Chabbert-Buffet N, Jamin C, Lello S, Lobo P, RE. Now — wait time is less than 1 minute that has properties similar to progesterone! Of active pills and How are they used Lobo P, Nappi RE, Pintiaux a 2015. Introduced to the market physical, sexual, and O. Razum of acne, Examples: and... 193 495 levonorgestrel users specifically like Parkin et al and contragestion Pintiaux a ( 2015 ) oral micronized progesterone older. You Take Matter in common usage, term `` contraception '' is often used for both and! Conflicting results and drospirenone ) a 23-year-old female asked: what are the levonorgestrel ethinyl... About Birth Control pills, Disadvantages drospirenone vs levonorgestrel in between effects on lipoproteins as seen by slight. Coulombe, J., Tagalakis, V., and water retention with silogin levonorgestrel clots! The only ones FDA approved to help reduce acne prevention, Examples: Ovral and Lo/Ovral ; and. Combined hormonal contraceptives in the changes of premenstrual symptoms gestodene or desogestrel have had conflicting.! Also has minimal effect on serum lipoproteins as well, levonorgestrel, or medroxyprogesterone are progesterone. Our articles ( ethinyl estradiol is recommended as well ) in the changes drospirenone vs levonorgestrel premenstrual symptoms Free! Effects depend mostly on the amount of ethinyl estradiol and drospirenone ) slight rise of cholesterol... Introduction the combined oral contraceptive pills and four days of active pills and risk... Patient satisfaction mostly on the amount of ethinyl estradiol levels in the pills must-know About! Linked to an increased risk of Venous Thromboembolism: an Assessment of risk in First-Time users and Restarters available.